AB063. Potential synergistic effect by combination of PED-4 and PED-5 inhibitors plus theophylline in lung cancer?

BACKGROUND: Lung cancer remains the leading cause of cancer-related deaths worldwide and novel therapeutic approaches targeting crucial pathways are urgently needed to improve its treatment. Differentiation-based therapeutics (Methylxanthines) and phosphodiesterase inhibitors (type 4 and 5), have be...

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Veröffentlicht in:Ann Transl Med
Hauptverfasser: Domvri, Kalliopi, Hohenforst-Schmidt, Wolfgang, Zogas, Nikolaos, Petanidis, Savvas, Zarogoulidis, Paul, Porpodis, Konstantinos, Kioseoglou, Efi, Zarogoulidis, Konstantinos
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2016
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Abstract
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159351/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.AB063
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