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Total Biosynthesis for Milligram-Scale Production of Etoposide Intermediates in a Plant Chassis
Etoposide is a plant-derived drug used clinically to treat several forms of cancer. Recent shortages of etoposide demonstrate the need for a more dependable production method to replace the semisynthetic method currently in place, which relies on extraction of a precursor natural product from Himala...
Enregistré dans:
| Publié dans: | J Am Chem Soc |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380830/ https://ncbi.nlm.nih.gov/pubmed/31755709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10717 |
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