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Total Biosynthesis for Milligram-Scale Production of Etoposide Intermediates in a Plant Chassis
Etoposide is a plant-derived drug used clinically to treat several forms of cancer. Recent shortages of etoposide demonstrate the need for a more dependable production method to replace the semisynthetic method currently in place, which relies on extraction of a precursor natural product from Himala...
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| Vydáno v: | J Am Chem Soc |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380830/ https://ncbi.nlm.nih.gov/pubmed/31755709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10717 |
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