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C-terminal residues of activated protein C light chain contribute to its anticoagulant and cytoprotective activities
BACKGROUND: Activated protein C (APC) is an important homeostatic blood coagulation protease that conveys anticoagulant and cytoprotective activities. Proteolytic inactivation of factors Va and VIIIa facilitated by cofactor protein S is responsible for APC’s anticoagulant effects, whereas cytoprotec...
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| Udgivet i: | J Thromb Haemost |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380734/ https://ncbi.nlm.nih.gov/pubmed/32017367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14756 |
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