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Protein C anticoagulant and cytoprotective pathways

Plasma protein C is a serine protease zymogen that is transformed into the active, trypsin-like protease, activated protein C (APC), which can exert multiple activities. For its anticoagulant action, APC causes inactivation of the procoagulant cofactors, factors Va and VIIIa, by limited proteolysis,...

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Detalhes bibliográficos
Main Authors: Griffin, John H, Zlokovic, Berislav V, Mosnier, Laurent O
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413316/
https://ncbi.nlm.nih.gov/pubmed/22477541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-012-1059-0
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