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Neurotoxicity of the anticoagulant-selective E149A-activated protein C variant after focal ischemic stroke in mice
Wild type (wt) activated protein C (APC) and cytoprotective-selective APC variants such as 3K3A-APC (< 10% anticoagulant but normal cytoprotective activity) are neuroprotective in murine focal ischemic stroke models. Here we compared the neuroprotective effects of the anticoagulant-selective E149...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812054/ https://ncbi.nlm.nih.gov/pubmed/23541526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2013.02.009 |
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