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Allo-network drugs: harnessing allostery in cellular networks

Allosteric drugs are increasingly used because they produce fewer side effects. Allosteric signal propagation does not stop at the ‘end’ of a protein, but may be dynamically transmitted across the cell. We propose here that the concept of allosteric drugs can be broadened to ‘allo-network drugs’ – w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Trends Pharmacol Sci
Egile Nagusiak: Nussinov, Ruth, Tsai, Chung-Jung, Csermely, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380718/
https://ncbi.nlm.nih.gov/pubmed/21925743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.08.004
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