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Allo-network drugs: harnessing allostery in cellular networks
Allosteric drugs are increasingly used because they produce fewer side effects. Allosteric signal propagation does not stop at the ‘end’ of a protein, but may be dynamically transmitted across the cell. We propose here that the concept of allosteric drugs can be broadened to ‘allo-network drugs’ – w...
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| Veröffentlicht in: | Trends Pharmacol Sci |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7380718/ https://ncbi.nlm.nih.gov/pubmed/21925743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.08.004 |
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