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Dynamic Allostery: Linkers Are Not Merely Flexible
Most proteins consist of multiple domains. How do linkers efficiently transfer information between sites that are on different domains to activate the protein? Mere flexibility only implies that the conformations would be sampled. For fast timescales between triggering events and cellular response,...
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| Publicado en: | Structure |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6361528/ https://ncbi.nlm.nih.gov/pubmed/21742258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.06.002 |
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