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Dynamic Allostery: Linkers Are Not Merely Flexible

Most proteins consist of multiple domains. How do linkers efficiently transfer information between sites that are on different domains to activate the protein? Mere flexibility only implies that the conformations would be sampled. For fast timescales between triggering events and cellular response,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Structure
Prif Awduron: Ma, Buyong, Tsai, Chung-Jung, Haliloğlu, Türkan, Nussinov, Ruth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361528/
https://ncbi.nlm.nih.gov/pubmed/21742258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.06.002
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