Using Serum Metabolomics to Predict Development of Anti-drug Antibodies in Multiple Sclerosis Patients Treated With IFNβ

Background: Neutralizing anti-drug antibodies (ADA) can greatly reduce the efficacy of biopharmaceuticals used to treat patients with multiple sclerosis (MS). However, the biological factors pre-disposing an individual to develop ADA are poorly characterized. Thus, there is an unmet clinical need fo...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Waddington, Kirsty E., Papadaki, Artemis, Coelewij, Leda, Adriani, Marsilio, Nytrova, Petra, Kubala Havrdova, Eva, Fogdell-Hahn, Anna, Farrell, Rachel, Dönnes, Pierre, Pineda-Torra, Inés, Jury, Elizabeth C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380268/
https://ncbi.nlm.nih.gov/pubmed/32765529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01527
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