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Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function

It is well established that cholesterol and glycosphingolipids are enriched in the plasma membrane (PM) and form signaling platforms called lipid rafts, essential for T-cell activation and function. Moreover, changes in PM lipid composition affect the biophysical properties of lipid rafts and have a...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Robinson, George A., Waddington, Kirsty E., Pineda-Torra, Ines, Jury, Elizabeth C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705553/
https://ncbi.nlm.nih.gov/pubmed/29225604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01636
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