Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor

Retinoid X receptor (RXR) plays a pivotal role as a transcriptional regulator and serves as an obligatory heterodimerization partner for at least 20 other nuclear receptors (NRs). Given a potentially limiting/sequestered pool of RXR and simultaneous expression of several RXR partners, we hypothesize...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Fadel, Lina, Rehó, Bálint, Volkó, Julianna, Bojcsuk, Dóra, Kolostyák, Zsuzsanna, Nagy, Gergely, Müller, Gabriele, Simandi, Zoltan, Hegedüs, Éva, Szabó, Gábor, Tóth, Katalin, Nagy, Laszlo, Vámosi, György
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380180/
https://ncbi.nlm.nih.gov/pubmed/32513869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011614
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