Ligand Binding Shifts Highly Mobile Retinoid X Receptor to the Chromatin-Bound State in a Coactivator-Dependent Manner, as Revealed by Single-Cell Imaging

Retinoid X receptor (RXR) is a promiscuous nuclear receptor forming heterodimers with several other receptors, which activate different sets of genes. Upon agonist treatment, the occupancy of its genomic binding regions increased, but only a modest change in the number of sites was revealed by chrom...

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Bibliografische gegevens
Hoofdauteurs: Brazda, Peter, Krieger, Jan, Daniel, Bence, Jonas, David, Szekeres, Tibor, Langowski, Jörg, Tóth, Katalin, Nagy, Laszlo, Vámosi, György
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993562/
https://ncbi.nlm.nih.gov/pubmed/24449763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01097-13
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