IL-2 and IL-15 receptor α-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells

The private α-chains of IL-2 and IL-15 receptors (IL-2R and IL-15R) share the signaling β- and γ(c)-subunits, resulting in both common and contrasting roles of IL-2 and IL-15 in T cell function. Knowledge of the cytokine-dependent subunit assembly is indispensable for understanding the paradox of di...

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Autors principals: Vámosi, György, Bodnár, Andrea, Vereb, György, Jenei, Attila, Goldman, Carolyn K., Langowski, Jörg, Tóth, Katalin, Mátyus, László, Szöllösi, János, Waldmann, Thomas A., Damjanovich, Sándor
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC503744/
https://ncbi.nlm.nih.gov/pubmed/15263076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403916101
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