IL-2 and IL-15 receptor α-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells
The private α-chains of IL-2 and IL-15 receptors (IL-2R and IL-15R) share the signaling β- and γ(c)-subunits, resulting in both common and contrasting roles of IL-2 and IL-15 in T cell function. Knowledge of the cytokine-dependent subunit assembly is indispensable for understanding the paradox of di...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC503744/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15263076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403916101 |
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