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Membrane Potential Distinctly Modulates Mobility and Signaling of IL-2 and IL-15 Receptors in T Cells

The high electric field across the plasma membrane might influence the conformation and behavior of transmembrane proteins that have uneven charge distributions in or near their transmembrane regions. Membrane depolarization of T cells occurs in the tumor microenvironment and in inflamed tissues bec...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Nagy, Éva, Mocsár, Gábor, Sebestyén, Veronika, Volkó, Julianna, Papp, Ferenc, Tóth, Katalin, Damjanovich, Sándor, Panyi, György, Waldmann, Thomas A., Bodnár, Andrea, Vámosi, György
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129476/
https://ncbi.nlm.nih.gov/pubmed/29754714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.04.038
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