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Membrane Potential Distinctly Modulates Mobility and Signaling of IL-2 and IL-15 Receptors in T Cells

The high electric field across the plasma membrane might influence the conformation and behavior of transmembrane proteins that have uneven charge distributions in or near their transmembrane regions. Membrane depolarization of T cells occurs in the tumor microenvironment and in inflamed tissues bec...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Nagy, Éva, Mocsár, Gábor, Sebestyén, Veronika, Volkó, Julianna, Papp, Ferenc, Tóth, Katalin, Damjanovich, Sándor, Panyi, György, Waldmann, Thomas A., Bodnár, Andrea, Vámosi, György
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129476/
https://ncbi.nlm.nih.gov/pubmed/29754714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.04.038
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