A chemical inhibitor of heat shock protein 78 (HSP78) from Leishmania donovani represents a potential antileishmanial drug candidate

The emergence of resistance to available antileishmanial drugs advocates identification of new drug targets and their inhibitors for visceral leishmaniasis. Here, we identified Leishmania donovani heat shock protein 78 (LdHSP78), a putative caseinolytic protease, as important for parasite infection...

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Опубликовано в: :J Biol Chem
Главные авторы: Das, Sonali, Banerjee, Anindyajit, Kamran, Mohd, Ejazi, Sarfaraz Ahmad, Asad, Mohammad, Ali, Nahid, Chakrabarti, Saikat
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2020
Предметы:
Microbiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380179/
https://ncbi.nlm.nih.gov/pubmed/32471865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014587
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