A chemical inhibitor of heat shock protein 78 (HSP78) from Leishmania donovani represents a potential antileishmanial drug candidate

The emergence of resistance to available antileishmanial drugs advocates identification of new drug targets and their inhibitors for visceral leishmaniasis. Here, we identified Leishmania donovani heat shock protein 78 (LdHSP78), a putative caseinolytic protease, as important for parasite infection...

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Publicado en:J Biol Chem
Autores principales: Das, Sonali, Banerjee, Anindyajit, Kamran, Mohd, Ejazi, Sarfaraz Ahmad, Asad, Mohammad, Ali, Nahid, Chakrabarti, Saikat
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380179/
https://ncbi.nlm.nih.gov/pubmed/32471865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014587
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