A chemical inhibitor of heat shock protein 78 (HSP78) from Leishmania donovani represents a potential antileishmanial drug candidate

The emergence of resistance to available antileishmanial drugs advocates identification of new drug targets and their inhibitors for visceral leishmaniasis. Here, we identified Leishmania donovani heat shock protein 78 (LdHSP78), a putative caseinolytic protease, as important for parasite infection...

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Vydáno v:J Biol Chem
Hlavní autoři: Das, Sonali, Banerjee, Anindyajit, Kamran, Mohd, Ejazi, Sarfaraz Ahmad, Asad, Mohammad, Ali, Nahid, Chakrabarti, Saikat
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380179/
https://ncbi.nlm.nih.gov/pubmed/32471865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014587
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