A chemical inhibitor of heat shock protein 78 (HSP78) from Leishmania donovani represents a potential antileishmanial drug candidate

The emergence of resistance to available antileishmanial drugs advocates identification of new drug targets and their inhibitors for visceral leishmaniasis. Here, we identified Leishmania donovani heat shock protein 78 (LdHSP78), a putative caseinolytic protease, as important for parasite infection...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Das, Sonali, Banerjee, Anindyajit, Kamran, Mohd, Ejazi, Sarfaraz Ahmad, Asad, Mohammad, Ali, Nahid, Chakrabarti, Saikat
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7380179/
https://ncbi.nlm.nih.gov/pubmed/32471865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014587
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