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5xFAD mice display sex-dependent inflammatory gene induction during the prodromal stage of Alzheimer’s disease

Alzheimer’s disease (AD) pathology consists of extracellular deposits of amyloid-β peptides (Aβ) and intracellular neurofibrillary tangles. These pathological alterations are accompanied by a neuroinflammatory response consisting of increased expression of inflammatory mediators. An anti-inflammator...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Manji, Zahra, Rojas, Asheebo, Wang, Wenyi, Dingledine, Raymond, Varvel, Nicholas H., Ganesh, Thota
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379326/
https://ncbi.nlm.nih.gov/pubmed/31322556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180678
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