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The Distinct Role of Tcfs and Lef1 in the Self-Renewal or Differentiation of Mouse Embryonic Stem Cells

BACKGROUND AND OBJECTIVES: Tcfs and Lef1 are DNA-binding transcriptional factors in the canonical Wnt signaling pathway. In the absence of β-catenin, Tcfs and Lef1 generally act as transcriptional repressors with co-repressor proteins such as Groucho, CtBP, and HIC-5. However, Tcfs and Lef1 turn int...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Stem Cells
Main Authors: Kim, Sewoon, Kim, Hanjun, Tan, Anderson, Song, Yonghee, Lee, Hyeju, Ying, Qi-Long, Jho, Eek-hoon
פורמט: Artigo
שפה:Inglês
יצא לאור: Korean Society for Stem Cell Research 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378906/
https://ncbi.nlm.nih.gov/pubmed/32587136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc20044
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