Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells

Activation of Wnt signaling enhances self-renewal of mouse embryonic and neural stem/progenitor cells. In contrast, undifferentiated ES cells show a very low level of endogenous Wnt signaling, and ectopic activation of Wnt signaling has been shown to block neuronal differentiation. Therefore, it rem...

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Detalles Bibliográficos
Publicado en:Stem Cells Int
Main Authors: Kim, Hanjun, Kim, Sewoon, Song, Yonghee, Kim, Wantae, Ying, Qi-Long, Jho, Eek-hoon
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402205/
https://ncbi.nlm.nih.gov/pubmed/25945099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/459301
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