Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells

Activation of Wnt signaling enhances self-renewal of mouse embryonic and neural stem/progenitor cells. In contrast, undifferentiated ES cells show a very low level of endogenous Wnt signaling, and ectopic activation of Wnt signaling has been shown to block neuronal differentiation. Therefore, it rem...

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Dades bibliogràfiques
Publicat a:Stem Cells Int
Autors principals: Kim, Hanjun, Kim, Sewoon, Song, Yonghee, Kim, Wantae, Ying, Qi-Long, Jho, Eek-hoon
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402205/
https://ncbi.nlm.nih.gov/pubmed/25945099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/459301
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