Investigating the pathogenic SNPs in BLM helicase and their biological consequences by computational approach

The BLM helicase protein plays a vital role in DNA replication and the maintenance of genomic integrity. Variation in the BLM helicase gene resulted in defects in the DNA repair mechanism and was reported to be associated with Bloom syndrome (BS) and cancer. Despite extensive investigation of helica...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Alzahrani, Faisal A., Ahmed, Firoz, Sharma, Monika, Rehan, Mohd, Mahfuz, Maryam, Baeshen, Mohammed N., Hawsawi, Yousef, Almatrafi, Ahmed, Alsagaby, Suliman Abdallah, Kamal, Mohammad Azhar, Warsi, Mohiuddin Khan, Choudhry, Hani, Jamal, Mohammad Sarwar
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378827/
https://ncbi.nlm.nih.gov/pubmed/32704157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69033-8
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