The CD28 Transmembrane Domain Contains an Essential Dimerization Motif

CD28 plays a critical role in regulating immune responses both by enhancing effector T cell activation and differentiation and controlling the development and function of regulatory T cells. CD28 is expressed at the cell surface as a disulfide linked homodimer that is thought to bind ligand monovale...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Leddon, Scott A., Fettis, Margaret M., Abramo, Kristin, Kelly, Ryan, Oleksyn, David, Miller, Jim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378745/
https://ncbi.nlm.nih.gov/pubmed/32765524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01519
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