Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis

BACKGROUND: This study aims to explore relationships between baseline demographic covariates, plasma antibiotic exposure, sputum bacillary load, and clinical outcome data to help improve future tuberculosis (TB) treatment response predictions. METHODS: Data were available from a longitudinal cohort...

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Publicat a:Open Forum Infect Dis
Autors principals: Kloprogge, Frank, Mwandumba, Henry C, Banda, Gertrude, Kamdolozi, Mercy, Shani, Doris, Corbett, Elizabeth L, Kontogianni, Nadia, Ward, Steve, Khoo, Saye H, Davies, Geraint R, Sloan, Derek J
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Major Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378673/
https://ncbi.nlm.nih.gov/pubmed/32733976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa218
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