Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

Background. Antibiotic-tolerant bacterial persistence prevents treatment shortening in drug-susceptible tuberculosis, and accumulation of intracellular lipid bodies has been proposed to identify a persister phenotype of Mycobacterium tuberculosis cells. In Malawi, we modeled bacillary elimination ra...

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Detaylı Bibliyografya
Yayımlandı:Clin Infect Dis
Asıl Yazarlar: Sloan, Derek J., Mwandumba, Henry C., Garton, Natalie J., Khoo, Saye H., Butterworth, Anthony E., Allain, Theresa J., Heyderman, Robert S., Corbett, Elizabeth L., Barer, Mike R., Davies, Geraint R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Articles and Commentaries
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463005/
https://ncbi.nlm.nih.gov/pubmed/25778753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ195
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