YWHAE/14-3-3ε expression impacts the protein load, contributing to proteasome inhibitor sensitivity in multiple myeloma

High protein load is a feature of multiple myeloma (MM), making the disease exquisitely sensitive to proteasome inhibitor (PIs). Despite the success of PIs in improving patient outcome, the majority of patients develop resistance leading to progressive disease; thus, the need to investigate the mech...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Xu, Yan, Fulciniti, Mariateresa, Samur, Mehmet K., Ho, Matthew, Deng, Shuhui, Liu, Lanting, Wen, Kenneth, Yu, Tengteng, Chyra, Zuzana, Dereibal, Sanika, Zhang, Li, Yao, Yao, Chakraborty, Chandraditya, Morelli, Eugenio, Li, Na, Lopez, Michael A., Perini, Tommaso, Mu, Shidai, An, Gang, Alonso, Rafael, Bianchi, Giada, Tai, Yu-Tzu, Anderson, Kenneth C., Qiu, Lugui, Munshi, Nikhil C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378455/
https://ncbi.nlm.nih.gov/pubmed/32187357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004147
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