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Analyzing kinetic signaling data for G-protein-coupled receptors
In classical pharmacology, bioassay data are fit to general equations (e.g. the dose response equation) to determine empirical drug parameters (e.g. EC(50) and E(max)), which are then used to calculate chemical parameters such as affinity and efficacy. Here we used a similar approach for kinetic, ti...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7378232/ https://ncbi.nlm.nih.gov/pubmed/32704081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67844-3 |
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