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Analyzing kinetic signaling data for G-protein-coupled receptors
In classical pharmacology, bioassay data are fit to general equations (e.g. the dose response equation) to determine empirical drug parameters (e.g. EC(50) and E(max)), which are then used to calculate chemical parameters such as affinity and efficacy. Here we used a similar approach for kinetic, ti...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7378232/ https://ncbi.nlm.nih.gov/pubmed/32704081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67844-3 |
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