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p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis

Neonatal mice and adult zebrafish can fully regenerate their hearts through proliferation of pre-existing cardiomyocytes. Previous studies have revealed that p53 signalling is activated during cardiac regeneration in neonatal mice and that hydrogen peroxide (H(2)O(2)) generated near the wound site a...

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Publicado en:Cell Death Dis
Autores principales: Ye, Shengfan, Zhao, Ting, Zhang, Wei, Tang, Zimu, Gao, Ce, Ma, Zhipeng, Xiong, Jing-Wei, Peng, Jinrong, Tan, Wei-Qiang, Chen, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378207/
https://ncbi.nlm.nih.gov/pubmed/32703938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02781-7
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