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Specific targeting of IL-1β activity to CD8(+) T cells allows for safe use as a vaccine adjuvant

Annual administration and reformulation of influenza vaccines is required for protection against seasonal infections. However, the induction of strong and long-lasting T cells is critical to reach broad and potentially lifelong antiviral immunity. The NLRP3 inflammasome and its product interleukin-1...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Van Den Eeckhout, Bram, Van Hoecke, Lien, Burg, Elianne, Van Lint, Sandra, Peelman, Frank, Kley, Niko, Uzé, Gilles, Saelens, Xavier, Tavernier, Jan, Gerlo, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378068/
https://ncbi.nlm.nih.gov/pubmed/32714571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00211-5
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