An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally, prompting an international effort to accelerate development of a vaccine. The candidate vaccine mRNA-1273 encodes the stabilized prefusion SARS-CoV-2 spike protein. METHODS: We cond...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Jackson, Lisa A., Anderson, Evan J., Rouphael, Nadine G., Roberts, Paul C., Makhene, Mamodikoe, Coler, Rhea N., McCullough, Michele P., Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian, Flach, Britta, Doria-Rose, Nicole A., Corbett, Kizzmekia S., Morabito, Kaitlyn M., O’Dell, Sijy, Schmidt, Stephen D., Swanson, Phillip A., Padilla, Marcelino, Mascola, John R., Neuzil, Kathleen M., Bennett, Hamilton, Sun, Wellington, Peters, Etza, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Buchanan, Wendy, Pikaart-Tautges, Rhonda, Ledgerwood, Julie E., Graham, Barney S., Beigel, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Massachusetts Medical Society 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377258/
https://ncbi.nlm.nih.gov/pubmed/32663912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2022483
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