Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

SARS-CoV-2 mutations may diminish vaccine-induced protective immune responses, and the durability of such responses has not been previously reported. Here, we present a comprehensive assessment of the impact of variants B.1.1.7, B.1.351, P.1, B.1.429, and B.1.526 on binding, neutralizing, and ACE2-b...

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Foilsithe in:bioRxiv
Main Authors: Pegu, Amarendra, O’Connell, Sarah, Schmidt, Stephen D, O’Dell, Sijy, Talana, Chloe A., Lai, Lilin, Albert, Jim, Anderson, Evan, Bennett, Hamilton, Corbett, Kizzmekia S., Flach, Britta, Jackson, Lisa, Leav, Brett, Ledgerwood, Julie E., Luke, Catherine J., Makowski, Mat, Roberts, Paul C., Roederer, Mario, Rebolledo, Paulina A., Rostad, Christina A., Rouphael, Nadine G., Shi, Wei, Wang, Lingshu, Widge, Alicia T., Yang, Eun Sung, Beigel, John H., Graham, Barney S., Mascola, John R, Suthar, Mehul S., McDermott, Adrian, Doria-Rose, Nicole A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory 2021
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142657/
https://ncbi.nlm.nih.gov/pubmed/34031659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.13.444010
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