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Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants

SARS-CoV-2 mutations may diminish vaccine-induced protective immune responses, and the durability of such responses has not been previously reported. Here, we present a comprehensive assessment of the impact of variants B.1.1.7, B.1.351, P.1, B.1.429, and B.1.526 on binding, neutralizing, and ACE2-b...

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Bibliografiske detaljer
Udgivet i:bioRxiv
Main Authors: Pegu, Amarendra, O’Connell, Sarah, Schmidt, Stephen D, O’Dell, Sijy, Talana, Chloe A., Lai, Lilin, Albert, Jim, Anderson, Evan, Bennett, Hamilton, Corbett, Kizzmekia S., Flach, Britta, Jackson, Lisa, Leav, Brett, Ledgerwood, Julie E., Luke, Catherine J., Makowski, Mat, Roberts, Paul C., Roederer, Mario, Rebolledo, Paulina A., Rostad, Christina A., Rouphael, Nadine G., Shi, Wei, Wang, Lingshu, Widge, Alicia T., Yang, Eun Sung, Beigel, John H., Graham, Barney S., Mascola, John R, Suthar, Mehul S., McDermott, Adrian, Doria-Rose, Nicole A.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8142657/
https://ncbi.nlm.nih.gov/pubmed/34031659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.05.13.444010
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