An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally, prompting an international effort to accelerate development of a vaccine. The candidate vaccine mRNA-1273 encodes the stabilized prefusion SARS-CoV-2 spike protein. METHODS: We cond...

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Détails bibliographiques
Publié dans:N Engl J Med
Auteurs principaux: Jackson, Lisa A., Anderson, Evan J., Rouphael, Nadine G., Roberts, Paul C., Makhene, Mamodikoe, Coler, Rhea N., McCullough, Michele P., Chappell, James D., Denison, Mark R., Stevens, Laura J., Pruijssers, Andrea J., McDermott, Adrian, Flach, Britta, Doria-Rose, Nicole A., Corbett, Kizzmekia S., Morabito, Kaitlyn M., O’Dell, Sijy, Schmidt, Stephen D., Swanson, Phillip A., Padilla, Marcelino, Mascola, John R., Neuzil, Kathleen M., Bennett, Hamilton, Sun, Wellington, Peters, Etza, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Buchanan, Wendy, Pikaart-Tautges, Rhonda, Ledgerwood, Julie E., Graham, Barney S., Beigel, John H.
Format: Artigo
Langue:Inglês
Publié: Massachusetts Medical Society 2020
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377258/
https://ncbi.nlm.nih.gov/pubmed/32663912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2022483
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