Novel transcription regulatory sequences and factors of the immune evasion protein ICP47 (US12) of herpes simplex viruses

BACKGROUND: Herpes simplex virus (HSV) can cause encephalitis. Its infected cell polypeptide 47 (ICP47), encoded by immediate-early gene US12, promotes immune escape. ICP47 was modified in the clinically approved oncolytic HSV (oHSV) T-Vec. However, transcription regulatory sequence (TRS) and transc...

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Dades bibliogràfiques
Publicat a:Virol J
Autors principals: Cheng, Jun-Ting, Wang, Ying-Ying, Zhu, Lin-Zhong, Zhang, Ying, Cai, Wen-Qi, Han, Zi-Wen, Zhou, Yang, Wang, Xian-Wang, Peng, Xiao-Chun, Xiang, Ying, Yang, Hui-Yu, Cui, Shu-Zhong, Ma, Zhaowu, Liu, Bing-Rong, Xin, Hong-Wu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377220/
https://ncbi.nlm.nih.gov/pubmed/32650799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01365-3
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