Novel transcription regulatory sequences and factors of the immune evasion protein ICP47 (US12) of herpes simplex viruses

BACKGROUND: Herpes simplex virus (HSV) can cause encephalitis. Its infected cell polypeptide 47 (ICP47), encoded by immediate-early gene US12, promotes immune escape. ICP47 was modified in the clinically approved oncolytic HSV (oHSV) T-Vec. However, transcription regulatory sequence (TRS) and transc...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Cheng, Jun-Ting, Wang, Ying-Ying, Zhu, Lin-Zhong, Zhang, Ying, Cai, Wen-Qi, Han, Zi-Wen, Zhou, Yang, Wang, Xian-Wang, Peng, Xiao-Chun, Xiang, Ying, Yang, Hui-Yu, Cui, Shu-Zhong, Ma, Zhaowu, Liu, Bing-Rong, Xin, Hong-Wu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7377220/
https://ncbi.nlm.nih.gov/pubmed/32650799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01365-3
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