Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human

Receptor-mediated transcytosis (RMT) is a principal pathway for transport of macromolecules essential for brain function across the blood–brain barrier (BBB). Antibodies or peptide ligands which bind RMT receptors are often co-opted for brain delivery of biotherapeutics. Constitutively recycling tra...

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Библиографические подробности
Опубликовано в: :Fluids Barriers CNS
Главные авторы: Zhang, Wandong, Liu, Qing Yan, Haqqani, Arsalan S., Leclerc, Sonia, Liu, Ziying, Fauteux, François, Baumann, Ewa, Delaney, Christie E., Ly, Dao, Star, Alexandra T., Brunette, Eric, Sodja, Caroline, Hewitt, Melissa, Sandhu, Jagdeep K., Stanimirovic, Danica B.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376922/
https://ncbi.nlm.nih.gov/pubmed/32698806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-020-00209-0
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