Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier

Current methods for examining antibody trafficking are either non-quantitative such as immunocytochemistry or require antibody labeling with tracers. We have developed a multiplexed quantitative method for antibody ‘tracking’ in endosomal compartments of brain endothelial cells. Rat brain endothelia...

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Dettagli Bibliografici
Pubblicato in:J Cereb Blood Flow Metab
Autori principali: Haqqani, Arsalan S, Delaney, Christie E, Brunette, Eric, Baumann, Ewa, Farrington, Graham K, Sisk, William, Eldredge, John, Ding, Wen, Tremblay, Tammy-Lynn, Stanimirovic, Danica B
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888858/
https://ncbi.nlm.nih.gov/pubmed/29140158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17740031
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