Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human

Receptor-mediated transcytosis (RMT) is a principal pathway for transport of macromolecules essential for brain function across the blood–brain barrier (BBB). Antibodies or peptide ligands which bind RMT receptors are often co-opted for brain delivery of biotherapeutics. Constitutively recycling tra...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Zhang, Wandong, Liu, Qing Yan, Haqqani, Arsalan S., Leclerc, Sonia, Liu, Ziying, Fauteux, François, Baumann, Ewa, Delaney, Christie E., Ly, Dao, Star, Alexandra T., Brunette, Eric, Sodja, Caroline, Hewitt, Melissa, Sandhu, Jagdeep K., Stanimirovic, Danica B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376922/
https://ncbi.nlm.nih.gov/pubmed/32698806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-020-00209-0
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