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dUMP/F-dUMP Binding to Thymidylate Synthase: Human Versus Mycobacterium tuberculosis

[Image: see text] Thymidylate synthase is an enzyme that catalyzes deoxythymidine monophosphate (dTMP) synthesis from substrate deoxyuridine monophosphate (dUMP). Thymidylate synthase of Mycobacterium tuberculosis (MtbThyX) is structurally distinct from its human analogue human thymidylate synthase...

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Bibliografische gegevens
Gepubliceerd in:ACS Omega
Hoofdauteurs: Gaurav, Kumar, Adhikary, Tiasha, Satpati, Priyadarshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2020
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376888/
https://ncbi.nlm.nih.gov/pubmed/32715203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01224
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