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dUMP/F-dUMP Binding to Thymidylate Synthase: Human Versus Mycobacterium tuberculosis

[Image: see text] Thymidylate synthase is an enzyme that catalyzes deoxythymidine monophosphate (dTMP) synthesis from substrate deoxyuridine monophosphate (dUMP). Thymidylate synthase of Mycobacterium tuberculosis (MtbThyX) is structurally distinct from its human analogue human thymidylate synthase...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Gaurav, Kumar, Adhikary, Tiasha, Satpati, Priyadarshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376888/
https://ncbi.nlm.nih.gov/pubmed/32715203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c01224
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