Dchs1-Fat4 regulation of osteogenic differentiation in mouse

In human, mutations of the protocadherins FAT4 and DCHS1 result in Van Maldergem syndrome, which is characterised, in part, by craniofacial abnormalities. Here, we analyse the role of Dchs1-Fat4 signalling during osteoblast differentiation in mouse. We show that Fat4 and Dchs1 mutants mimic the cran...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Crespo-Enriquez, Ivan, Hodgson, Tina, Zakaria, Sana, Cadoni, Erika, Shah, Mittal, Allen, Stephen, Al-Khishali, Ayman, Mao, Yaopan, Yiu, Angela, Petzold, Jonna, Villagomez-Olea, Guillermo, Pitsillides, Andrew A., Irvine, Kenneth D., Francis-West, Philippa
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376788/
https://ncbi.nlm.nih.gov/pubmed/31358536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.176776
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