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Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development

The Drosophila Dachsous and Fat proteins function as ligand and receptor, respectively, for an intercellular signaling pathway that regulates Hippo signaling and planar cell polarity. Although gene-targeted mutations in two mammalian Fat genes have been described, whether mammals have a Fat signalin...

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Detalles Bibliográficos
Main Authors: Mao, Yaopan, Mulvaney, Joanna, Zakaria, Sana, Yu, Tian, Morgan, Katherine Malanga, Allen, Steve, Basson, M. Albert, Francis-West, Philippa, Irvine, Kenneth D.
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035097/
https://ncbi.nlm.nih.gov/pubmed/21303848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.057166
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