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Dchs1-Fat4 regulation of osteogenic differentiation in mouse

In human, mutations of the protocadherins FAT4 and DCHS1 result in Van Maldergem syndrome, which is characterised, in part, by craniofacial abnormalities. Here, we analyse the role of Dchs1-Fat4 signalling during osteoblast differentiation in mouse. We show that Fat4 and Dchs1 mutants mimic the cran...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Crespo-Enriquez, Ivan, Hodgson, Tina, Zakaria, Sana, Cadoni, Erika, Shah, Mittal, Allen, Stephen, Al-Khishali, Ayman, Mao, Yaopan, Yiu, Angela, Petzold, Jonna, Villagomez-Olea, Guillermo, Pitsillides, Andrew A., Irvine, Kenneth D., Francis-West, Philippa
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376788/
https://ncbi.nlm.nih.gov/pubmed/31358536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.176776
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