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In vitro and in vivo human metabolism and pharmacokinetics of S‐ and R‐praziquantel
Racemic praziquantel (PZQ) is the drug of choice for the treatment of schistosomiasis. R‐Praziquantel (R‐PZQ) has been shown as the therapeutic form, whereas S‐PZQ is less efficacious and responsible for the bitter taste of the tablet. This study aimed at investigating the metabolism of R‐ and S‐PZQ...
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| Veröffentlicht in: | Pharmacol Res Perspect |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376644/ https://ncbi.nlm.nih.gov/pubmed/32700798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.618 |
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