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Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral leishmaniasis

The development of an effective oral therapeutics is an immediate need for the control and elimination of visceral leishmaniasis (VL). We exemplify the preparation and optimization of 2-hydroxypropyl-β-cyclodextrin (HPCD) modified solid lipid nanoparticles (SLNs) based oral combinational cargo syste...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Parvez, Shabi, Yadagiri, Ganesh, Gedda, Mallikarjuna Rao, Singh, Aakriti, Singh, Om Prakash, Verma, Anurag, Sundar, Shyam, Mudavath, Shyam Lal
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376178/
https://ncbi.nlm.nih.gov/pubmed/32699361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69276-5
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