Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral leishmaniasis

The development of an effective oral therapeutics is an immediate need for the control and elimination of visceral leishmaniasis (VL). We exemplify the preparation and optimization of 2-hydroxypropyl-β-cyclodextrin (HPCD) modified solid lipid nanoparticles (SLNs) based oral combinational cargo syste...

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Published in:Sci Rep
Main Authors: Parvez, Shabi, Yadagiri, Ganesh, Gedda, Mallikarjuna Rao, Singh, Aakriti, Singh, Om Prakash, Verma, Anurag, Sundar, Shyam, Mudavath, Shyam Lal
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376178/
https://ncbi.nlm.nih.gov/pubmed/32699361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69276-5
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