Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral leishmaniasis

The development of an effective oral therapeutics is an immediate need for the control and elimination of visceral leishmaniasis (VL). We exemplify the preparation and optimization of 2-hydroxypropyl-β-cyclodextrin (HPCD) modified solid lipid nanoparticles (SLNs) based oral combinational cargo syste...

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Pubblicato in:Sci Rep
Autori principali: Parvez, Shabi, Yadagiri, Ganesh, Gedda, Mallikarjuna Rao, Singh, Aakriti, Singh, Om Prakash, Verma, Anurag, Sundar, Shyam, Mudavath, Shyam Lal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376178/
https://ncbi.nlm.nih.gov/pubmed/32699361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69276-5
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