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Connecting Coil-to-Globule Transitions to Full Phase Diagrams for Intrinsically Disordered Proteins

Phase separation is thought to underlie spatial and temporal organization that is required for controlling biochemical reactions in cells. Multivalence of interaction motifs, also known as stickers, is a defining feature of proteins that drive phase separation. Intrinsically disordered proteins with...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Zeng, Xiangze, Holehouse, Alex S., Chilkoti, Ashutosh, Mittag, Tanja, Pappu, Rohit V.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376131/
https://ncbi.nlm.nih.gov/pubmed/32619404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.014
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