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GWAS for lifespan and decline in climbing ability in flies upon dietary restriction reveal decima as a mediator of insulin-like peptide production

Dietary restriction (DR) is the most robust means to extend lifespan and delay age-related diseases across species. An underlying assumption in the aging field is that DR enhances both lifespan and physical activity through similar mechanisms, but this has not been rigorously tested in different gen...

詳細記述

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書誌詳細
出版年:Curr Biol
主要な著者: Wilson, Kenneth A., Beck, Jennifer N., Nelson, Christopher S., Hilsabeck, Tyler A., Promislow, Daniel, Brem, Rachel B., Kapahi, Pankaj
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375902/
https://ncbi.nlm.nih.gov/pubmed/32502405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.05.020
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